TREATMENT OF NEONATAL LUPUS - CASE-REPORT AND REVIEW OF THE LITERATURE

被引：0
作者：
RIDER, LG
BUYON, JP
RUTLEDGE, J
SHERRY, DD
机构：
[1] UNIV WASHINGTON,CHILDRENS ORTHOPED HOSP & MED CTR,DEPT PEDIAT,DIV RHEUMATOL,SEATTLE,WA 98105
[2] UNIV WASHINGTON,CHILDRENS ORTHOPED HOSP & MED CTR,DEPT LAB MED,DIV RHEUMATOL,SEATTLE,WA 98105
来源：
JOURNAL OF RHEUMATOLOGY | 1993年 / 20卷 / 07期
关键词：
NEONATAL LUPUS SYNDROME; CONGENITAL COMPLETE HEART BLOCK; IMMUNOSUPPRESSIVE THERAPY; STEROIDS; PLASMAPHERESIS; EXCHANGE TRANSFUSION;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A critically ill infant with congenital complete heart block and neonatal lupus was treated with pulse steroids, exchange transfusion and intravenous gammaglobulin. Transient improvement in clinical status and laboratory results occurred, although the infant died. Based on this report and review of prior experience with immunosuppressive therapy, prenatal treatment of the mother with betamethasone or dexamethasone has been successful in resolving the cardiomyopathy/myocarditis associated with neonatal lupus. Postnatal treatment of the infant with steroids appears to be beneficial for persistent hepatic and hematologic manifestations. The evidence for exchange transfusion is less certain.
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收藏
页码：1208 / 1211
页数：4
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