THE SIGNIFICANCE OF PROSTAGLANDIN-F2-ALPHA (PGFM) AND OXYTOCIN PLASMA-LEVELS IN PRETERM LABOR PATIENTS

被引:0
作者
VAVRA, N [1 ]
SEVELDA, P [1 ]
FITZ, R [1 ]
EPPEL, W [1 ]
FUCHS, AR [1 ]
FUCHS, F [1 ]
HUSSLEIN, P [1 ]
机构
[1] CORNELL UNIV,MED CTR,COLL MED,DEPT OBSTET & GYNECOL,NEW YORK,NY 10021
关键词
D O I
10.1055/s-2007-1023792
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
In the present study, plasma oxytocin and prostaglandin F2 alpha metabolite (PGFM) concentrations were measured in 46 patients admitted for preterm labour. Gestational age ranged from 20-34 weeks. Samples were collected 12 hours before and after initiation of tocolysis. Patients with a premature rupture of the membranes and/or intra-amniotic infection were excluded in this study. There was a significant difference in the oxytocin (p=0.05) and PGFM levels (p=0.007, after 12 hours: p=0.004) between a control group without preterm labour and women with preterm labour. No differences were seen between the successfully treated (delivery more than 5 days after start of tocolysis) and the failure group. There was no significantly different increase or decrease in PGFM and Oxytocin plasma levels between treatment failures and successfully treated patients.
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页码:475 / 478
页数:4
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