Hepatitis B virus reactivation with a rituximab-containing regimen

被引:60
作者
Tsutsumi, Yutaka [1 ]
Yamamoto, Yoshiya [2 ]
Ito, Shinichi [1 ]
Ohigashi, Hiroyuki [1 ]
Shiratori, Souichi [1 ]
Naruse, Hirohito [2 ]
Teshima, Takanori [3 ]
机构
[1] Hakodate Municipal Hosp, Dept Hematol, 1-10-1 Minato Cho, Hakodate, Hokkaido 0418680, Japan
[2] Hakodate Municipal Hosp, Dept Gastroenterol, Hakodate, Hokkaido 0418680, Japan
[3] Hokkaido Univ, Grad Sch Med, Dept Hematol, Sapporo, Hokkaido 0600808, Japan
关键词
Rituximab; Hepatitis B virus; Reactivation; Nucleoside analog; Non-Hodgkin's lymphoma;
D O I
10.4254/wjh.v7.i21.2344
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Rituximab is currently used not only in the treatment of B-cell lymphoma but also for various other diseases, including autoimmune diseases, post-transplant graft vs host disease, and rejection following kidney transplants. Due to rituximab's widespread use, great progress has been made regarding research into complications that arise from its use, one of the most serious being the reactivation of hepatitis B virus (HBV), and efforts continue to establish guidelines for preventive treatment against this occurrence. This report discusses preventive measures against rituximab-induced HBV reactivation and future objectives.
引用
收藏
页码:2344 / 2351
页数:8
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