Incidence of peptic ulcer is about 2-3/1000 and its prevalence 17/1000. Hospitalizations for ulcer are stable at 30-40/100 000 inhabitants. About 70% of patients hospitalized for peptic ulcer complications are over 60 years of age and 80% of deaths occur in individuals aged more than 65. The main association for ulcer and bleeding is the intake of NSAIDS. This symposium analyzes various diagnostic and therapeutic aspects of peptic ulcer bleeding.