POSSIBLE ROLE FOR WATER DISSOCIATION IN THE SLOW BINDING OF PHOSPHORUS-CONTAINING TRANSITION-STATE-ANALOGUE INHIBITORS OF THERMOLYSIN

被引：134
作者：
BARTLETT, PA
MARLOWE, CK
机构：
来源：
BIOCHEMISTRY | 1987年 / 26卷 / 26期
关键词：
D O I：
10.1021/bi00400a009
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：8553 / 8561
页数：9
相关论文
共 52 条
[1]   INHIBITION OF CHYMOTRYPSIN BY PHOSPHONATE AND PHOSPHONAMIDATE PEPTIDE ANALOGS [J].
BARTLETT, PA ;
LAMDEN, LA .
BIOORGANIC CHEMISTRY, 1986, 14 (04) :356-377
[2]   EVALUATION OF INTRINSIC BINDING-ENERGY FROM A HYDROGEN-BONDING GROUP IN AN ENZYME-INHIBITOR [J].
BARTLETT, PA ;
MARLOWE, CK .
SCIENCE, 1987, 235 (4788) :569-571
[3]   PHOSPHONAMIDATES AS TRANSITION-STATE ANALOG INHIBITORS OF THERMOLYSIN [J].
BARTLETT, PA ;
MARLOWE, CK .
BIOCHEMISTRY, 1983, 22 (20) :4618-4624
[4]  
BARTLETT PA, 1970, TETRAHEDRON LETT, P4459
[5]  
BENEDETTI E, 1983, INT J PEPT PROT RES, V21, P163
[6]   INVESTIGATION OF DIFFUSION-LIMITED RATES OF CHYMOTRYPSIN REACTIONS BY VISCOSITY VARIATION [J].
BROUWER, AC ;
KIRSCH, JF .
BIOCHEMISTRY, 1982, 21 (06) :1302-1307
[7]   TIGHT-BINDING INHIBITORS .1. KINETIC-BEHAVIOR [J].
CHA, S .
BIOCHEMICAL PHARMACOLOGY, 1975, 24 (23) :2177-2185
[8]  
CHA S, 1976, BIOCHEM PHARMACOL, V25, P1561
[9]   TIGHT-BINDING INHIBITORS .3. NEW APPROACH FOR DETERMINATION OF COMPETITION BETWEEN TIGHT-BINDING INHIBITORS AND SUBSTRATES-INHIBITION OF ADENOSINE-DEAMINASE BY COFORMYCIN [J].
CHA, S .
BIOCHEMICAL PHARMACOLOGY, 1976, 25 (24) :2695-2702
[10]   COMPUTER PROGRAMMES FOR PROCESSING ENZYME KINETIC DATA [J].
CLELAND, WW .
NATURE, 1963, 198 (487) :463-+
123456