ASSESSMENT IN RATS OF A NEW BIOERODIBLE BONE-WAX-LIKE POLYMER

被引：21

作者：

SUDMANN, B

ANFINSEN, OG

BANG, G

KOPPANG, R

STOLEN, SO

KOPPANG, HS

SUDMANN, E

机构：

[1] UNIV OSLO,FAC DENT,DEPT PATHOL,OSLO 3,NORWAY

[2] UNIV OSLO,FAC DENT,DEPT PRECLIN TECHNIQUES & MAT SCI,OSLO 3,NORWAY

[3] UNIV BERGEN,SCH DENT,SURG RES LAB,N-5014 BERGEN,NORWAY

[4] UNIV BERGEN,SCH DENT,DEPT ORAL PATHOL & FORENS ODONT,N-5014 BERGEN,NORWAY

来源：

ACTA ORTHOPAEDICA SCANDINAVICA | 1993年 / 64卷 / 03期

关键词：

D O I：

10.3109/17453679308993639

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Holes drilled in rats' skull, iliac crest, and tibia were filled with beeswax or with a new, wax-like, bioerodible polyorthoester (Alzamer(R)). Empty drill-holes served as controls. In addition, beeswax and polyorthoester were deposited between the left and the right oblique abdominal muscles, respectively. In muscle, both the beeswax and polyorthoester elicited a transient foreign body reaction. The beeswax was not resorbed in bone or muscle, whereas the polyorthoester was. Bone healing was inhibited in the iliac crest and the tibiae filled with beeswax, whereas holes filled with polyorthoester healed readily.

引用

页码：336 / 339

页数：4

共 18 条

[1] FOREIGN-BODY REACTION TO BONE WAX - REPORT OF A CASE [J].

AURELIO, J ;

CHENAIL, B ;

GERSTEIN, H .

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, 1984, 58 (01) :98-100

[2]

Brightmore T G, 1975, Langenbecks Arch Chir, VSuppl, P39

[3]

CAPOZZA RC, 1978, POLYM DELIVERY SYSTE, P59

[4] FRACTURE-HEALING IN RATS INHIBITED BY LOCALLY ADMINISTERED INDOMETHACIN [J].

ENGESAETER, LB ;

SUDMANN, B ;

SUDMANN, E .

ACTA ORTHOPAEDICA SCANDINAVICA, 1992, 63 (03) :330-333

[5] RELEASE OF NORETHINDRONE FROM POLY(ORTHO ESTERS) [J].

HELLER, J ;

PENHALE, DWH ;

HELWING, RF ;

FRITZINGER, BK .

POLYMER ENGINEERING AND SCIENCE, 1981, 21 (11) :727-731

[6]

HORSLEY V, 1892, BRIT MED J, V1, P1165

[7]

Howard T C, 1969, Clin Orthop Relat Res, V63, P226

[8]

JOHNSON P, 1981, SURGERY, V89, P206

[9]

Parker R, 1892, BRIT MED J, V1, P1076

[10] BONE INDUCTION BY COMPOSITE OF BIOERODIBLE POLYORTHOESTER AND DEMINERALIZED BONE-MATRIX IN RATS [J].

PINHOLT, EM ;

SOLHEIM, E ;

BANG, G ;

SUDMANN, E .

ACTA ORTHOPAEDICA SCANDINAVICA, 1991, 62 (05) :476-480

← 1 2 →