SKIN RASH, FEVER AND RIGORS CAUSED BY OLSALAZINE

被引：0

作者：

FINNIE, IA ^{[1
]}

GILMORE, IT ^{[1
]}

机构：

[1] ROYAL LIVERPOOL UNIV HOSP,GASTROENTEROL UNIT,PRESCOT ST,LIVERPOOL L7 8XP,ENGLAND

来源：

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY | 1993年 / 5卷 / 10期

关键词：

ULCERATIVE COLITIS; TREATMENT; SIDE EFFECTS; FEVER; SKIN RASH; OLSALAZINE; 5-AMINOSALICYLIC ACID;

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Objective: To report a case where a patient receiving olsalazine for control of ulcerative colitis developed high fever with rigors and a skin rash. Patient: A 61-year-old man with ulcerative colitis who was known to be intolerant to sulphasalazine. Results: Symptoms resolved rapidly following withdrawal of olsalazine. The patient was discharged and on follow-up 3 months later reported no further fever, rigors or malaise. Conclusions: The rapid improvement in symptoms following cessation of therapy with olsalazine is suggestive of hypersensitivity to either 5-aminosalicylic acid or its acetylated form. This case reinforces the need to be cautious when 5-aminosalicylic acid is used in patients known to be intolerant to sulphasalazine.

引用

页码：881 / 883

页数：3