NONVIRAL GENE-THERAPY

被引:40
|
作者
TRECO, DA
SELDEN, RF
机构
[1] TKT Incorporated, Cambridge, MA 02139
来源
MOLECULAR MEDICINE TODAY | 1995年 / 1卷 / 07期
关键词
D O I
10.1016/S1357-4310(95)80030-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Gene therapy is a medical/surgical intervention currently being developed, in which genes are introduced into cells in order to treat or cure a wide variety of human diseases, The field has evolved over the past four decades, with most experimental gene-therapy studies based on the use of viruses to deliver the genes of therapeutic interest, More recently, a large number of non-viral approaches to gene therapy have emerged, yielding promising pre-clinical results, and which are currently being evaluated in early stage clinical trials.
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页码:314 / 321
页数:8
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