REVERSED-PHASE CHROMATOGRAPHY OF SMALL MOLECULES AND PEPTIDES ON A CONTINUOUS ROD OF MACROPOROUS POLY(STYRENE-CO-DIVINYLBENZENE)

被引:165
|
作者
WANG, QC [1 ]
SVEC, F [1 ]
FRECHET, JMJ [1 ]
机构
[1] CORNELL UNIV,DEPT CHEM,BAKER LAB,ITHACA,NY 14853
关键词
D O I
10.1016/0021-9673(94)80352-8
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A continuous ''molded'' rod of porous poly(styrene-co-divinylbenzene) prepared by a bulk free radical polymerization within the confines of a chromatagraphic column has been used successfully for the reversed-phase HPLC of alkylbenzenes and peptides. An excellent rapid separation of bradykinin and [D-Phe(7)]-bradykinin with a molecular mass of about 1000 was also achieved.
引用
收藏
页码:230 / 235
页数:6
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