REGIONAL LOCALIZATION OF THE INTESTINAL MUCIN GENE MUC3 TO CHROMOSOME 7Q22

被引：40

作者：

FOX, MF ^{[1
]}

LAHBIB, F ^{[1
]}

PRATT, W ^{[1
]}

ATTWOOD, J ^{[1
]}

GUM, J ^{[1
]}

KIM, Y ^{[1
]}

SWALLOW, DM ^{[1
]}

机构：

[1] VET ADM MED CTR,GASTROINTESTINAL RES LAB,SAN FRANCISCO,CA 94121

来源：

ANNALS OF HUMAN GENETICS | 1992年 / 56卷

关键词：

D O I：

10.1111/j.1469-1809.1992.tb01154.x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The gene MUC3 which codes for a mucin expressed in intestine (Gum et al. 1990) has previously been mapped, using somatic cell hybrids, to chromosome 7. We describe here the regional localization of MUC3 to chromosome 7q22 by in situ hybridization. Preliminary linkage analysis using CEPH (Centre d'Etude du Polymorphisme Humain) families supports this assignment and places MUC3 in the same linkage group as COL1A2 and CFTR.

引用

页码：281 / 287

页数：7

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