IDENTIFICATION OF A SACCHAROMYCES-CEREVISIAE HOMOLOG OF THE SNF2 TRANSCRIPTIONAL REGULATOR IN THE DNA-SEQUENCE OF AN 8.6 KB REGION IN THE LTE1-CYS1 INTERVAL ON THE LEFT ARM OF CHROMOSOME-I

被引：32
作者：
CLARK, MW
ZHONG, WW
KENG, T
STORMS, RK
BARTON, A
KABACK, DB
BUSSEY, H
机构：
[1] MCGILL UNIV,DEPT BIOL,MONTREAL H3A 1B1,QUEBEC,CANADA
[2] MCGILL UNIV,SCH MED,DEPT MICROBIOL & IMMUNOL,MONTREAL H3A 2B4,QUEBEC,CANADA
[3] CONCORDIA UNIV,DEPT BIOL,MONTREAL H3G 1M8,QUEBEC,CANADA
[4] UNIV MED & DENT NEW JERSEY,NEW JERSEY MED SCH,DEPT MICROBIOL & MOLEC GENET,NEWARK,NJ 07103
[5] MCGILL CONCORDIA YEAST GENOME GRP,MONTREAL,QUEBEC,CANADA
来源：
YEAST | 1992年 / 8卷 / 02期
关键词：
SACCHAROMYCES-CEREVISIAE; CHROMOSOME-I; SEQUENCE; TRANSCRIPTIONAL REGULATORS;
D O I：
10.1002/yea.320080208
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The DNA sequence of an 8.6 kb region of the left arm of chromosome I has been determined. This region, between the LTE1 and CYS1 loci, is approximately 40 kb from the centromere. There are six potential open-reading frames (ORFs), provisionally named YAL001-006 within this fragment of chromosome I. Four of these ORFs can be aligned with previously identified FUN transcripts: FUN28 with YAL006, FUN29 with YAL004, FUN30 with YAL001 and FUN31 with YAL002. The YAL001 ORF shows significant homology to the SNF2 transcriptional regulator. A region of the DNA contains an extensive repeat of the bases C-A-T positioned in the 5' terminus of the YAL004 promoter region.
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页码：133 / 145
页数：13
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