LONG HIV-1 INCUBATION PERIODS AND DYNAMICS OF TRANSMISSION WITHIN A FAMILY

被引：26

作者：

BURGER, H

BELMAN, AL

GRIMSON, R

KAELL, A

FLAHERTY, K

GULLA, J

GIBBS, RA

NGUYUN, PN

WEISER, B

机构：

[1] SUNY STONY BROOK,DEPT MED,DIV RHEUMATOL,STONY BROOK,NY 11794

[2] SUNY STONY BROOK,DEPT MICROBIOL,STONY BROOK,NY 11794

[3] SUNY STONY BROOK,DEPT NEUROL,STONY BROOK,NY 11794

[4] SUNY STONY BROOK,DEPT PREVENT MED,STONY BROOK,NY 11794

[5] BAYLOR UNIV,INST MED GENET,HOUSTON,TX 77030

来源：

LANCET | 1990年 / 336卷 / 8708期

关键词：

D O I：

10.1016/0140-6736(90)91657-V

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The incubation period of human immuno-deficiency virus type 1 (HIV-1) infection was studied in a family of five in which vertical and heterosexual transmission occurred from one index case. This investigation documented incubation periods of longer than 12 years in a mother and her daughter; although neither has symptoms, both are definitely infected and have very low CD4+-lymphocyte counts. The study confirmed the predictions of incubation periods longer than 10 years in a small proportion of infected individuals. It provides evidence that vertically HIV-1-infected teenagers can be expected to appear in the population. © 1990.

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页码：134 / 136

页数：3

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