LONG HIV-1 INCUBATION PERIODS AND DYNAMICS OF TRANSMISSION WITHIN A FAMILY

被引：26
作者：
BURGER, H
BELMAN, AL
GRIMSON, R
KAELL, A
FLAHERTY, K
GULLA, J
GIBBS, RA
NGUYUN, PN
WEISER, B
机构：
[1] SUNY STONY BROOK,DEPT MED,DIV RHEUMATOL,STONY BROOK,NY 11794
[2] SUNY STONY BROOK,DEPT MICROBIOL,STONY BROOK,NY 11794
[3] SUNY STONY BROOK,DEPT NEUROL,STONY BROOK,NY 11794
[4] SUNY STONY BROOK,DEPT PREVENT MED,STONY BROOK,NY 11794
[5] BAYLOR UNIV,INST MED GENET,HOUSTON,TX 77030
来源：
LANCET | 1990年 / 336卷 / 8708期
关键词：
D O I：
10.1016/0140-6736(90)91657-V
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The incubation period of human immuno-deficiency virus type 1 (HIV-1) infection was studied in a family of five in which vertical and heterosexual transmission occurred from one index case. This investigation documented incubation periods of longer than 12 years in a mother and her daughter; although neither has symptoms, both are definitely infected and have very low CD4+-lymphocyte counts. The study confirmed the predictions of incubation periods longer than 10 years in a small proportion of infected individuals. It provides evidence that vertically HIV-1-infected teenagers can be expected to appear in the population. © 1990.
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页码：134 / 136
页数：3
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