TYROSINE-ALPHA-KETOGLUTARATE TRANSAMINASE - INDUCTION BY EPINEPHRINE AND ADENOSINE-3',5'-CYCLIC PHOSPHATE

被引：113

作者：

WICKS, WD

机构：

[1] Biology Division, NCI-AEC Carcinogenesis Program, Oak Ridge National Laboratory, Oak Ridge

来源：

SCIENCE | 1968年 / 160卷 / 3831期

关键词：

D O I：

10.1126/science.160.3831.997

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Epinephrine and the N6-O2′-dibutyryl analog of adenosine-3′,5′-cyclic phosphate both are effective inducers of tyrosine-α-ketoglutarate transaminase in explants of fetal rat liver maintained in organ culture. Combinations of these inducers with each other and with hydrocortisone, another inducer, yielded results which suggest that cyclic adenylic acid is an intermediate in the induction by epinephrine and that the mechanism by which it induces is different from that by which hydrocortisone operates.

引用

页码：997 / &

共 12 条

[1] ASSAY OF TYROSINE TRANSAMINASE ACTIVITY BY CONVERSION OF P-HYDROXYPHENYLPYRUVATE TO P-HYDROXYBENZALDEHYDE [J].