SYNOVIAL SARCOMA - A DNA FLOW CYTOMETRIC STUDY

被引：0
|
作者：
ELNAGGAR, AK
AYALA, AG
ABDULKARIM, FW
MCLEMORE, D
BALLANCE, WW
GARNSEY, L
RO, JY
BATSAKIS, JG
机构：
[1] UNIV TEXAS,MD ANDERSON HOSP & TUMOR INST,DEPT VET MED,HOUSTON,TX 77030
[2] UNIV TEXAS,MD ANDERSON HOSP & TUMOR INST,DEPT BIOMATH,HOUSTON,TX 77030
[3] CASE WESTERN RESERVE UNIV,CLEVELAND,OH 44106
来源：
CANCER | 1990年 / 65卷 / 10期
关键词：
D O I：
10.1002/1097-0142(19900515)65:10<2295::AID-CNCR2820651022>3.0.CO;2-7
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The relationship between DNA content, clinicopathologic findings, and patient survival in synovial sarcoma was investigated. Patient age at diagnosis (P < 0.001), tumor size (P < 0.001), and ploidy status (P < 0.003) correlated significantly with patient survival. A marginally significant correlation between mitotic count and patient survival was also observed (P = 0.04). Histologic subtypes (monophasic versus biphasic), mitotic count, and S‐phase by flow cytometry had no significant influence on the clinical outcome of patients with synovial sarcoma in this study. The authors conclude that DNA ploidy analysis is a significant objective probe in the prognostication of patients with synovial sarcoma. Copyright © 1990 American Cancer Society
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页码：2295 / 2300
页数：6
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