The management of work-related asthma guidelines: a broader perspective

被引:61
作者
Baur, Xaver [1 ]
Aasen, Tor Brovig [2 ]
Burge, P. Sherwood [3 ]
Heederik, Dick [4 ]
Henneberger, Paul K. [5 ]
Maestrellie, Piero [6 ]
Schluenssen, Vivi [7 ]
Vandenplas, Olivier [8 ]
Wilken, Dennis [1 ]
机构
[1] Univ Med Ctr Hamburg Eppendorf, Inst Occupat & Maritime Med, Seewartenstr 10, D-20459 Hamburg, Germany
[2] Haukeland Hosp, Dept Occupat Asthma, Bergen, Norway
[3] Heart England NHS Fdn Trust, Dept Resp Med, Birmingham, W Midlands, England
[4] Univ Utrecht, IRAS, Environm Epidemiol Div, Utrecht, Netherlands
[5] NIOSH, Ctr Dis Control & Prevent, Morgantown, WV USA
[6] Univ Padua, Dept Environm Med & Publ Hlth, Padua, Italy
[7] Aarhus Univ, Sch Publ Hlth, Dept Environm & Occupat Med, Aarhus, Denmark
[8] Catholic Univ Louvain, Mont Godinne Hosp, Dept Chest Med, Yvoir, Belgium
关键词
Agents; compensation; legal adjudication; occupational asthma; socioeconomic impact;
D O I
10.1183/09059180.00004711
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
The aim of the European Respiratory Society work- related asthma guidelines is to present the management and prevention options of work- related asthma and their effectiveness. Work-related asthma accounts for 5-25% of all adult asthma cases and is responsible for a significant socioeconomic burden. Several hundred occupational agents, mainly allergens but also irritants and substances with unknown pathological mechanisms, have been identified as causing work- related asthma. The essential message of these guidelines is that the management of work-related asthma can be considerably optimised based on the present knowledge of causes, risk factors, pathomechanisms, and realistic and effective interventions. To reach this goal we urgently require greatly intensified primary preventive measures and improved case management. There is now a substantial body of evidence supporting the implementation of comprehensive medical surveillance programmes for workers at risk. Those workers who fail surveillance programmes need to be referred to a clinician who can confirm or exclude an occupational cause. Once work-related asthma is confirmed, a revised risk assessment in the workplace is needed to prevent further cases. These new guidelines confirm and extend already existing statements and recommendations. We hope that these guidelines will initiate the much-needed research that is required to fill the gaps in our knowledge and to initiate substantial improvements in preventative measures.
引用
收藏
页码:125 / 139
页数:15
相关论文
共 166 条
[31]   Allergen and dust exposure as determinants of work-related symptoms and sensitization in a cohort of flour-exposed workers; a case-control analysis [J].
Cullinan, P ;
Cook, A ;
Nieuwenhuijsen, MJ ;
Sandiford, C ;
Tee, RD ;
Venables, KM ;
McDonald, JC ;
Taylor, AJN .
ANNALS OF OCCUPATIONAL HYGIENE, 2001, 45 (02) :97-103
[32]   WORK-RELATED SYMPTOMS, SENSITIZATION, AND ESTIMATED EXPOSURE IN WORKERS NOT PREVIOUSLY EXPOSED TO LABORATORY RATS [J].
CULLINAN, P ;
LOWSON, D ;
NIEUWENHUIJSEN, MJ ;
GORDON, S ;
TEE, RD ;
VENABLES, KM ;
MCDONALD, JC ;
TAYLOR, AJN .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 1994, 51 (09) :589-592
[33]   The prevention of occupational asthma [J].
Cullinan, P ;
Tarlo, S ;
Nemery, B .
EUROPEAN RESPIRATORY JOURNAL, 2003, 22 (05) :853-860
[34]   Allergen exposure, atopy and smoking as determinants of allergy to rats in a cohort of laboratory employees [J].
Cullinan, P ;
Cook, A ;
Gordon, S ;
Nieuwenhuijsen, MJ ;
Tee, RD ;
Venables, KM ;
McDonald, JC ;
Taylor, AJN .
EUROPEAN RESPIRATORY JOURNAL, 1999, 13 (05) :1139-1143
[35]   Occupational asthma: a community based study [J].
de Bono, J ;
Hudsmith, L .
OCCUPATIONAL MEDICINE-OXFORD, 1999, 49 (04) :217-219
[36]   Cytokine fingerprinting and hazard assessment of chemical respiratory allergy [J].
Dearman, RJ ;
Kimber, I .
JOURNAL OF APPLIED TOXICOLOGY, 2001, 21 (02) :153-163
[37]  
Dearman RJ, 1999, J APPL TOXICOL, V19, P299, DOI 10.1002/(SICI)1099-1263(199909/10)19:5<299::AID-JAT591>3.0.CO
[38]  
2-C
[39]  
Drummond MF, 1987, METHOD EC EVALUATION
[40]   Incidence of allergy and allergy symptoms among workers exposed to laboratory animals [J].
Elliott, L ;
Heederik, D ;
Marshall, S ;
Peden, D ;
Loomis, D .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2005, 62 (11) :766-771