CEREBRAL METABOLIC CHANGES IN DELAYED CARBON-MONOXIDE SEQUELAE STUDIED BY PROTON MR SPECTROSCOPY

被引：28

作者：

KAMADA, K ^{[1
]}

HOUKIN, K ^{[1
]}

AOKI, T ^{[1
]}

KOIWA, M ^{[1
]}

KASHIWABA, T ^{[1
]}

IWASAKI, Y ^{[1
]}

ABE, H ^{[1
]}

机构：

[1] HOKKAIDO UNIV,SCH MED,DEPT NEUROSURG,SAPPORO,HOKKAIDO 060,JAPAN

来源：

NEURORADIOLOGY | 1994年 / 36卷 / 02期

关键词：

CARBON MONOXIDE POISONING; DELAYED CARBON MONOXIDE SEQUELAE; PROTON MAGNETIC RESONANCE SPECTROSCOPY;

D O I：

10.1007/BF00588070

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The pathogenesis of delayed sequelae of carbon monoxide (CO) exposure is still unknown. We repeatedly examined a 55-year-old woman with the interval form of CO poisoning, using proton magnetic resonance spectroscopy (MRS). When the clinical picture was severe, MRS revealed markedly lowered N-acetyl-asparatate (NAA)/creatine and phosphocreatine (Cr) ratio and slightly increased choline containing compounds (Cho)/Cr ratio. Subsequently, NAA and Cho/Cr ratio tended to return to normal, reflecting clinical improvement. Proton MRS shows the previously unrecognised neuronal activity in CO poisoning and precisely reflects the severity of symptoms. We stress the superiority of proton MRS over the conventional radiological examinations in CO poisoning.

引用

页码：104 / 106

页数：3

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