INTERMOLECULAR ELECTRON-TRANSFER FROM QUINOPROTEINS AND ITS RELEVANCE TO BIOSENSOR TECHNOLOGY

被引：45

作者：

DAVIDSON, VL

JONES, LH

机构：

[1] Department of Biochemistry, University of Mississippi Medical Center, Jackson

来源：

ANALYTICA CHIMICA ACTA | 1991年 / 249卷 / 01期

基金：

美国国家卫生研究院;

关键词：

KINETIC ANALYSIS; AMPEROMETRY; BIOSENSORS; ELECTRON TRANSFER; QUINOPROTEINS; METHYLAMINE DEHYDROGENASE;

D O I：

10.1016/0003-2670(91)87028-6

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Long-range intermolecular electron transfer occurs between the redox centers of the quinoprotein methylamine dehydrogenase and the copper protein amicyanin. A steady-state kinetic assay was developed and used to describe factors that are relevant to this process. Kinetic, physical. and structural data on these proteins and the complexes which they form are providing a picture of how nature accomplishes long-range electron transfer through proteins, a process that is critical to the development of direct amperometric biosensors.

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收藏

页码：235 / 240

页数：6

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