INITIATION AND DURATION OF BREAST-FEEDING IN WOMEN RECEIVING ANTIEPILEPTICS

被引:32
作者
ITO, S
MORETTI, M
LIAU, M
KOREN, G
机构
[1] Motherisk Program, Division of Clinical Pharmacology and Toxicology, Department of Pediatrics
关键词
BREAST-FEEDING; DRUG; MATERNAL MEDICATION; ANTIEPILEPTICS; ADVERSE EFFECTS;
D O I
10.1016/0002-9378(95)90015-2
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
OBJECTIVE: our purpose was to characterize breast-feeding initiation and the duration of breast-feeding in women receiving antiepileptics. STUDY DESIGN: A cohort study was performed on 34 pregnant epileptic women receiving antiepileptics and 34 pregnant age-matched controls. RESULTS: Fifty percent of the group receiving antiepileptics chose breast-feeding as the initial feeding method, which was significantly less than the controls (85%, p = 0.004). The decision to choose initial feeding methods was closely associated with advice from physicians and other sources. The 17 women in the antiepileptics group who chose breast-feeding initially terminated breast-feeding significantly earlier than did the control group (4.7 +/- 2.6 vs 9.3 +/- 5.7 months post partum, p < 0.005). CONCLUSIONS: Mothers receiving antiepileptics tend to choose formula feeding. Even when they choose breast-feeding initially, its duration is shorter than usual. Consensus and guidelines on this matter among experts remain to be reflected on and effectively implemented in current medical practice.
引用
收藏
页码:881 / 886
页数:6
相关论文
共 11 条
[1]  
ANDERSON PO, 1991, CLIN PHARMACY, V10, P594
[2]   DRUGS IN HUMAN-MILK - CLINICAL PHARMACOKINETIC CONSIDERATIONS [J].
ATKINSON, HC ;
BEGG, EJ ;
DARLOW, BA .
CLINICAL PHARMACOKINETICS, 1988, 14 (04) :217-240
[3]  
BENNETT PN, 1988, DRUGS HUMAN LACTATIO, P329
[4]   BREAST-FEEDING AND HEALTH IN THE 1980S - A GLOBAL EPIDEMIOLOGIC REVIEW [J].
CUNNINGHAM, AS ;
JELLIFFE, DB ;
JELLIFFE, EFP .
JOURNAL OF PEDIATRICS, 1991, 118 (05) :659-666
[5]  
DELGADOESCUETA AV, 1992, NEUROLOGY, V42, P149
[6]   PROSPECTIVE FOLLOW-UP OF ADVERSE REACTIONS IN BREAST-FED INFANTS EXPOSED TO MATERNAL MEDICATION [J].
ITO, S ;
BLAJCHMAN, A ;
STEPHENSON, M ;
ELIOPOULOS, C ;
KOREN, G .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1993, 168 (05) :1393-1399
[7]   ROLE OF INFANT-FEEDING PRACTICES IN DEVELOPMENT OF CROHNS-DISEASE IN CHILDHOOD [J].
KOLETZKO, S ;
SHERMAN, P ;
COREY, M ;
GRIFFITHS, A ;
SMITH, C .
BRITISH MEDICAL JOURNAL, 1989, 298 (6688) :1617-1618
[8]  
KOREN G, 1986, CAN MED ASSOC J, V135, P1079
[9]  
SAMUELS SE, 1985, AM J CLIN NUTR, V44, P504
[10]  
TANAKA PA, 1987, CAN MED ASSOC J, V136, P940