ACID-BASE RESPONSES TO HIGH-VOLUME HEMOFILTRATION IN THE CRITICALLY ILL

被引：0
作者：
NIMMO, GR
MACKENZIE, SJ
WALKER, S
NICOL, M
GRANT, IS
机构：
[1] WESTERN GEN HOSP,INTENS THERAPY UNIT,CROWE RD,EDINBURGH EH4 2XU,MIDLOTHIAN,SCOTLAND
[2] ROYAL EDINBURGH & ASSOCIATED HOSP,DEPT CLIN BIOCHEM,EDINBURGH EH3 9HB,MIDLOTHIAN,SCOTLAND
[3] UNIV EDINBURGH,EDINBURGH EH8 9YL,MIDLOTHIAN,SCOTLAND
来源：
NEPHROLOGY DIALYSIS TRANSPLANTATION | 1993年 / 8卷 / 09期
关键词：
HEMOFILTRATION; ACUTE RENAL FAILURE; ACID-BASE DISTURBANCE;
D O I：
暂无
中图分类号：
R3 [基础医学]; R4 [临床医学];
学科分类号：
1001 ; 1002 ; 100602 ;
摘要：
We have studied the acid-base and cardiorespiratory effects of intermittent pumped high-volume venovenous haemofiltration (HVHF) using replacement fluid containing lactate as the source of bicarbonate in critically ill patients. We demonstrated significant hyperlactataemia throughout the procedure, but there was no deterioration in acid-base status, haemodynamics, or oxygen delivery. These observations suggest that the worsening of acidosis and the hypotension that have been described with this technique [1] can be avoided by appropriate monitoring and resuscitation prior to haemofiltration, and may be due to unrecognized inadequacies in the oxygen transport system.
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页码：854 / 857
页数：4
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