NEW TREATMENT STRATEGIES FOR BACTERIAL-MENINGITIS

被引：4

作者：

ROOS, KL

机构：

[1] Department of Neurology, Indianapolis, IN 46202

来源：

CLINICAL NEUROPHARMACOLOGY | 1993年 / 16卷 / 05期

关键词：

BACTERIAL MENINGITIS; DEXAMETHASONE; LEUKOCYTE MONOCLONAL ANTIBODIES; PENTOXIFYLLINE; NONSTEROIDAL ANTIINFLAMMATORY AGENTS; ANTICYTOKINE ANTIBODIES;

D O I：

10.1097/00002826-199310000-00001

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Over the last several years, the therapeutic approach to bacterial meningitis has been changing. The neurological complications of bacterial meningitis result from an inflammatory process that is initiated by the lysis of bacteria in the subarachnoid space by antibiotics; to alter the pathophysiologic events initiated by this lysis, adjunctive therapy to antimicrobial therapy has been investigated in experimental and clinical trials. This article reviews our present understanding of bacterial meningitis, the efficacy of dexamethasone in treatment, and the potential use of leukocyte monoclonal antibodies, pentoxifylline, nonsteroidal antiinflammatory agents, and anticytokine antibodies.

引用

页码：373 / 386

页数：14

共 40 条

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