INTESTINAL-ABSORPTION OF IMMUNE-COMPLEXES BY NEONATAL RATS - ROUTE OF ANTIGEN TRANSFER FROM MOTHER TO YOUNG

被引：85
作者：
ABRAHAMSON, DR
POWERS, A
RODEWALD, R
机构：
[1] Department of Biology, University of Virginia, Charlottesville
来源：
SCIENCE | 1979年 / 206卷 / 4418期
关键词：
D O I：
10.1126/science.493961
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Horseradish peroxidase (HRP) in the presence of specific immunoglobulin G antibody to HRP is selectively absorbed from the gut lumen and transferred by intestinal epithelial cells to the lamina propria in newborn rats. The HRP is not transferred in detectable amounts in the absence of the antibody. Transport of maternally derived antigen via antigen-antibody complexes may have important influences on the developing immune system in young mammals. Copyright © 1979 AAAS.
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页码：567 / 569
页数：3
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