ABOLITION BY OMEPRAZOLE OF ASPIRIN INDUCED GASTRIC-MUCOSAL INJURY IN MAN

被引：86
|
作者：
DANESHMEND, TK [1 ]
STEIN, AG [1 ]
BHASKAR, NK [1 ]
HAWKEY, CJ [1 ]
机构：
[1] UNIV NOTTINGHAM HOSP,DEPT THERAPEUT,NOTTINGHAM NG7 2UH,ENGLAND
来源：
GUT | 1990年 / 31卷 / 05期
关键词：
D O I：
10.1136/gut.31.5.514
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
This study investigates whether aspirin injury to the human gastric mucosa can be prevented by profound acid suppression with omeprazole, in a randomised, double blind, crossover design according to latin square. It was concluded that profound acid suppression can prevent aspirin induced gastric mucosal injury in normal subjects. This approach may prevent the development of peptic ulcers and their complications in patients taking aspirin and other non-steroidal anti-inflammatory drugs.
引用
收藏
页码：514 / 517
页数：4
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