CATALYTIC ANTIBODIES WITH LIPASE ACTIVITY AND R-SUBSTRATE OR S-SUBSTRATE SELECTIVITY

被引：152

作者：

JANDA, KD ^{[1
]}

BENKOVIC, SJ ^{[1
]}

LERNER, RA ^{[1
]}

机构：

[1] PENN STATE UNIV,DEPT CHEM,UNIVERSITY PK,PA 16802

来源：

SCIENCE | 1989年 / 244卷 / 4903期

关键词：

D O I：

10.1126/science.2717936

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：437 / 440

页数：4

共 43 条

[1] CATALYSIS OF A STEREOSPECIFIC BIMOLECULAR AMIDE SYNTHESIS BY AN ANTIBODY [J].

BENKOVIC, SJ ;

NAPPER, AD ;

LERNER, RA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (15) :5355-5358

[2]

BIANCHI D, 1988, J ORG CHEM, V53, P5534

[3]

BRUICE TC, 1966, BIOORG MECH, pCH1

[4] PREPARATIVE PRODUCTION OF OPTICALLY-ACTIVE ESTERS AND ALCOHOLS USING ESTERASE-CATALYZED STEREOSPECIFIC TRANS-ESTERIFICATION IN ORGANIC MEDIA [J].

CAMBOU, B ;

KLIBANOV, AM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (09) :2687-2692

[5] PHOTOSENSITIZED CLEAVAGE OF A THYMINE DIMER BY AN ANTIBODY [J].

COCHRAN, AG ;

SUGASAWARA, R ;

SCHULTZ, PG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (23) :7888-7890

[6] ANTIBODY CATALYSIS IN REVERSE MICELLES [J].

DURFOR, CN ;

BOLIN, RJ ;

SUGASAWARA, RJ ;

MASSEY, RJ ;

JACOBS, JW ;

SCHULTZ, PG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (26) :8713-8714

[7]

ENGUALL E, 1980, METHODS ENZYMOLOGY A, V70, P419

[8]

FERSHT A, 1966, ENZYME STRUCTURE MEC, pCH1

[9] CONCERTED GENERAL BASE AND BIFUNCTIONAL GENERAL ACID CATALYSIS OF THE AMINOLYSIS OF PHENYL ACETATE BY PYRAZOLE [J].

FISHBEIN, JC ;

BAUM, H ;

COX, MM ;

JENCKS, WP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (19) :5790-5800

[10] CATALYSIS OF CONCERTED REACTIONS BY ANTIBODIES - THE CLAISEN REARRANGEMENT [J].

HILVERT, D ;

CARPENTER, SH ;

NARED, KD ;

AUDITOR, MTM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (14) :4953-4955

← 1 2 3 4 5 →