SPORIDESMINS .8. ISOLATION AND STRUCTURE OF SPORIDESMIN-D AND SPORIDESMIN-F

被引：37

作者：

JAMIESON, WD

RAHMAN, R

TAYLOR, A

机构：

[1] National Research Cocunil of Canada, Atlantic Regional Laboratory, Halifax, NS

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1969年 / 11期

关键词：

D O I：

10.1039/j39690001564

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chromatography of crude extracts of cultures of Pithomyces chartarum on silicic acid has been shown to separate the biologically active sporidesmins from a group of inactive metabolites. One of these inactive compounds has been purified and shown to be the dimethyl thioether analogue of sporidesmin, named spordesmin-D. Evidence is presented for the structure of another inactive metabolite, sporidesmin-F, which has not been obtained in crystalline form. Sporidesmin has been converted into sporidesmin-D by treatment with sodium borohydride and methyl iodide.

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页码：1564 / &

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