RECOGNITION OF DIFFERENTIATION ANTIGENS OF SPERMATOGENESIS IN THE MOUSE BY USING ANTIBODIES FROM SPLEEN CELL-MYELOMA HYBRIDS AFTER SYNGENEIC IMMUNIZATION

被引：67
作者：
BECHTOL, KB [1 ]
BROWN, SC [1 ]
KENNETT, RH [1 ]
机构：
[1] UNIV PENN,DEPT HUMAN GENET,PHILADELPHIA,PA 19104
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1979年 / 76卷 / 01期
关键词：
D O I：
10.1073/pnas.76.1.363
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Two differentiation antigens of spermatogenesis in the mouse are defined by monoclonal antibodies from hybridomas produced between the myeloma P3-X63Ag8 and spleen lymphocytes immunized with syngeneic testis cells. These antigens are on testis cells, and not liver, kidney, brain, spleen, or whole ovary. They are species but not strain specific and trypsin sensitive but collagenase insensitive. On the basis of their appearance during the onset of spermatogenesis they appear to be differentiation antigens expressed during different but overlapping time windows during spermatogenesis.
引用
收藏
页码：363 / 367
页数：5
相关论文
共 16 条
12