CLINICAL AND NEURORADIOLOGICAL FINDINGS IN CEREBRAL GLIOMATOSIS, INCLUDING MAGNETIC-RESONANCE-IMAGING

We present three cases of GC, one belonging to the brainstem, and two belonging to the hemisphere type. Two cases were investigated by MRI. Tumour infiltration, while yielding only vague CT findings, was well demonstrated in MR studies where extensive hyperintense lesions were found in T2- and proton density images. In patients studied by MR these were localized within the white matter and corpus callosum. No enhancement was seen after administration of Gd- DTPA. These findings may strongly indicate the presence of gliomatosis cerebri, when clinical and laboratory data exclude inflammatory or neurodegenerative disease. Despite the good delineation of white matter changes stereotactic biopsy remains necessary to confirm the diagnosis of gliomatosis cerebri pathohistologically.