SIGNIFICANT ENANTIOSELECTIVITY IN ALANINE ESTER HYDROLYSIS CATALYZED BY IMIDAZOLE ATTACHED BETA-CYCLODEXTRINS

被引：17

作者：

HAMASAKI, K

UENO, A

机构：

来源：

CHEMISTRY LETTERS | 1995年 / 09期

关键词：

D O I：

10.1246/cl.1995.859

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Imidazole-appended beta-cyclodextrins, 3-deoxy-3-imidazolyl-beta-cyclodextrin (3Im-beta CyD) and 6-deoxy-6-imidazolyl-beta-cyclodextrin (6Tm-beta CyD) were synthesized as substrate selective enzyme mimics. 6Im-beta CyD shows marked enantioselectivity in the hydrolysis of Boc-alanine beta-nitrophenyl ester rather than 3Im-beta CyD. This selectivity could be interpreted by transition stability theory.

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页码：859 / 860

页数：2

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