IMMUNOREACTIVITY OF SKATE ELECTROCYTES TOWARDS MONOCLONAL-ANTIBODIES AGAINST HUMAN DYSTROPHIN AND DYSTROPHIN-RELATED (DMDL) PROTEIN

被引：1
|
作者：
DOWDALL, MJ [1 ]
ELLIS, JM [1 ]
MAN, NT [1 ]
MORRIS, GE [1 ]
机构：
[1] NE WALES INST,DIV RES,DEESIDE,CLWYD,WALES
来源：
NEUROSCIENCE LETTERS | 1992年 / 138卷 / 01期
关键词：
DYSTROPHIN; MONOCLONAL ANTIBODY; IMMUNOREACTIVITY; ELECTRIC ORGAN; ELECTROCYTE; SKATE; TORPEDO;
D O I：
10.1016/0304-3940(92)90464-I
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Monoclonal antibodies against human dystrophin have been used to demonstrate the existence of a dystrophin-like protein in the electrocytes of skate electric organ. This protein is also present in skate muscle and resembles that found in Torpedo electric organ. Monoclonal antibodies against a human autosomal homologue of dystrophin (DMDL protein) did not detect a similar protein in skate or Torpedo. Immunocytochemical staining of the innervated and non-innervated faces of the electrocyte membrane was obtained using the anti-dystrophin antibodies only.
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页码：27 / 31
页数：5
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