IMMUNOREACTIVITY OF SKATE ELECTROCYTES TOWARDS MONOCLONAL-ANTIBODIES AGAINST HUMAN DYSTROPHIN AND DYSTROPHIN-RELATED (DMDL) PROTEIN

被引：1

作者：

DOWDALL, MJ ^{[1
]}

ELLIS, JM ^{[1
]}

MAN, NT ^{[1
]}

MORRIS, GE ^{[1
]}

机构：

[1] NE WALES INST,DIV RES,DEESIDE,CLWYD,WALES

来源：

NEUROSCIENCE LETTERS | 1992年 / 138卷 / 01期

关键词：

DYSTROPHIN; MONOCLONAL ANTIBODY; IMMUNOREACTIVITY; ELECTRIC ORGAN; ELECTROCYTE; SKATE; TORPEDO;

D O I：

10.1016/0304-3940(92)90464-I

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Monoclonal antibodies against human dystrophin have been used to demonstrate the existence of a dystrophin-like protein in the electrocytes of skate electric organ. This protein is also present in skate muscle and resembles that found in Torpedo electric organ. Monoclonal antibodies against a human autosomal homologue of dystrophin (DMDL protein) did not detect a similar protein in skate or Torpedo. Immunocytochemical staining of the innervated and non-innervated faces of the electrocyte membrane was obtained using the anti-dystrophin antibodies only.

引用

页码：27 / 31

页数：5