A MOLECULAR MECHANICAL STUDY OF THE STRUCTURE OF POLY (ALPHA-AMINOISOBUTYRIC-ACID)

被引：50
作者：
ALEMAN, C
SUBIRANA, JA
PEREZ, JJ
机构：
[1] Dpto. D'enginyeria Quimica, Upc, Ets D'enginyers Industrials, Barcelona, 08028, Av. Diagonal
来源：
BIOPOLYMERS | 1992年 / 32卷 / 06期
关键词：
D O I：
10.1002/bip.360320605
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A molecular mechanical study has been carried out to determine the most favorable conformation of poly(Aib) both in solution and in the solid state. An energetic approach to the packing has been carried out by studying the stability of pairs of poly(Aib) chains. The study reveals a higher stability of a 3(10)-helix when forming part of a dimer whereas in isolated molecules the alpha-helix structure seems to be more stable depending on the length of the chain and dielectric constant of the environment.
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页码：621 / 631
页数：11
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