DIFFERENTATION WITHOUT MITOSIS IN DICTYOSTELIUM-DISCOIDEUM

被引：17
作者：
CAPPUCCINELLI, P
FIGHETTI, M
RUBINO, S
机构：
[1] Institute of Microbiology, University of Sassari, 07100 Sassari Sardinia,, Viale Mancini
来源：
CELL DIFFERENTIATION | 1979年 / 8卷 / 03期
关键词：
D O I：
10.1016/0045-6039(79)90051-4
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Dictyoselium discoideum Ax-2 amoebae incubated in the presence of the microtubule inhibitor nocodazole, irreversibly lost their ability to multiply. Nocodazole-treated cells remained viable and RNA and protein synthesis continued for at least 48 h. When nocodazole-treated amoebae were allowed to develop on Millipore filters or on agar slides they differentiated with some delay when compared with controls. These results show that mitosis, naturally present during the developmental cycle of Dictyostelium discoideum Ax-2, is not indispensible for differentiation. © 1979.
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页码：243 / 252
页数：10
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