SYNTHESIS OF N2,3-ETHENODEOXYGUANOSINE, N2,3-ETHENODEOXYGUANOSINE 5'-PHOSPHATE, AND N2,3-ETHENODEOXYGUANOSINE 5'-TRIPHOSPHATE - STABILITY OF THE GLYCOSYL BOND IN THE MONOMER AND IN POLY(DG, EPSILON-DG-DC)

被引：33
作者：
KUSMIEREK, JT
FOLKMAN, W
SINGER, B
机构：
[1] UNIV CALIF BERKELEY LAWRENCE BERKELEY LAB,DONNER LAB,BERKELEY,CA 94720
[2] POLISH ACAD SCI,INST BIOCHEM & BIOPHYS,PL-02532 WARSAW,POLAND
来源：
CHEMICAL RESEARCH IN TOXICOLOGY | 1989年 / 2卷 / 04期
关键词：
D O I：
10.1021/tx00010a003
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：230 / 233
页数：4
相关论文
共 18 条
[1]  
FEDTKE N, 1988, IN PRESS ARCH TOXICO
[2]  
GIZIEWICZ J, 1975, ACTA BIOCHIM POL, V22, P87
[3]   THE PARA-NITROPHENYLETHYL (NPE) GROUP - A VERSATILE NEW BLOCKING GROUP FOR PHOSPHATE AND AGLYCONE PROTECTION IN NUCLEOSIDES AND NUCLEOTIDES [J].
HIMMELSBACH, F ;
SCHULZ, BS ;
TRICHTINGER, T ;
CHARUBALA, R ;
PFLEIDERER, W .
TETRAHEDRON, 1984, 40 (01) :59-72
[4]   CONVERSION OF MONO- AND OLIGODEOXYRIBONUCLEOTIDES TO 5'-TRIPHOSPHATES [J].
HOARD, DE ;
OTT, DG .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1965, 87 (08) :1785-&
[5]   HYDROLYSIS OF NUCLEOSIDES RELATED TO WYOSINE [J].
ITAYA, T ;
HARADA, T .
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1984, (13) :858-859
[6]   GLYCOSYL CONFORMATIONAL AND INDUCTIVE EFFECTS ON ACID-CATALYZED HYDROLYSIS OF PURINE NUCLEOSIDES [J].
JORDAN, F ;
NIV, H .
NUCLEIC ACIDS RESEARCH, 1977, 4 (03) :697-709
[7]   KINETICS AND MECHANISMS OF HYDROLYTIC REACTIONS OF METHYLATED CYTIDINES UNDER ACIDIC AND NEUTRAL CONDITIONS [J].
KUSMIEREK, J ;
KAPPI, R ;
NEUVONEN, K ;
SHUGAR, D ;
LONNBERG, H .
ACTA CHEMICA SCANDINAVICA, 1989, 43 (02) :196-202
[8]   SYNTHESIS AND PROPERTIES OF N2,3-ETHENOGUANOSINE AND N2,3-ETHENOGUANOSINE 5'-DIPHOSPHATE [J].
KUSMIEREK, JT ;
JENSEN, DE ;
SPENGLER, SJ ;
STOLARSKI, R ;
SINGER, B .
JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (12) :2374-2378
[9]  
Laib R J, 1986, IARC Sci Publ, P101
[10]   STUDIES ON POLYNUCLEOTIDES .34. SPECIFIC SYNTHESIS OF C3]-C5]-LINKED RIBOOLIGONUCLEOTIDES . NEW PROTECTED DERIVATIVES OF RIBONUCLEOSIDES + RIBONUCLEOSIDE 3]-PHOSPHATES . FURTHER SYNTHESES OF DIRIBONUCLEOSIDE PHOSPHATES [J].
LOHRMANN, R ;
KHORANA, HG .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (19) :4188-&
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