DEXAMETHASONE CONCENTRATIONS AND THE DEXAMETHASONE SUPPRESSION TEST IN PSYCHIATRIC-DISORDERS

被引：76
作者：
MORRIS, H
CARR, V
GILLILAND, J
HOOPER, M
机构：
[1] INST MED & VET SCI, DIV CLIN CHEM, ADELAIDE, SA 5000, AUSTRALIA
[2] UNIV ADELAIDE, PSYCHIAT, ADELAIDE, SA 5000, AUSTRALIA
[3] ROYAL ADELAIDE HOSP, ADELAIDE, SA 5000, AUSTRALIA
来源：
BRITISH JOURNAL OF PSYCHIATRY | 1986年 / 148卷
关键词：
D O I：
10.1192/bjp.148.1.66
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
The dexamethasone suppression test (DST) has been widely used in psychiatry as a laboratory aid for the diagnosis of endogneous depression; failure to suppress serum cortisol levels is interpreted as confirming a clinical diagnosis of endogenous depression. We found that serum dexamethasone concentrations in this test vary widely and are determinants of the DST response: non-suppression of serum cortisol levels is associated with low serum dexamethasone concentrations, and suppression is associated with high concentrations.
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页码：66 / 69
页数：4
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