POROUS CELLULOSE MATRICES - A NOVEL EXCIPIENT FOR THE FORMULATION OF SOLID DOSAGE FORMS

被引：12
作者：
DAVIDSON, R [1 ]
NYQVIST, H [1 ]
RAGNARSSON, G [1 ]
机构：
[1] KABI PHARMACIA THERAPEUT AB,S-11287 STOCKHOLM,SWEDEN
来源：
INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1993年 / 100卷 / 1-3期
关键词：
MULTIPLE UNIT SYSTEM; DRUG CARRIER; CELLULOSE; MICROCRYSTALLINE CELLULOSE; POROUS BEAD; SPHERICAL MATRIX;
D O I：
10.1016/0378-5173(93)90074-P
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
A novel pharmaceutical aid prepared from a specially processed cellulose is presented. The material, which consists of highly porous spherical cellulose beads, is regarded as having a considerable field of application in dry pharmaceutical formulation. Primarily, the material may act as a multiple unit carrier and release controlling system as well as an additive for the compression of multiple unit preparations in the form of compressed and disintegrating tablets. This paper describes formulation possibilities, and presents some of the essential characteristics and preliminary results on some applications.
引用
收藏
页码：49 / 54
页数：6
相关论文
共 48 条
  • [41] Cellulose-based surface-modified heterogeneously feasible novel solid acid catalyst to access bioactive heterocycles
    Karhale, Shrikrishna
    Kadam, Ankush
    RESEARCH ON CHEMICAL INTERMEDIATES, 2024, 50 (01) : 31 - 48
  • [42] Novel modified microcrystalline cellulose-based porous material for fast and effective heavy-metal removal from aqueous solution
    Cao, Jie
    Fei, Dongtao
    Tian, Xiaoling
    Zhu, Yuejun
    Wang, Shanshan
    Zhang, Yadong
    Mao, Qiangqiang
    Sun, Mingbo
    CELLULOSE, 2017, 24 (12) : 5565 - 5577
  • [43] Novel modified microcrystalline cellulose-based porous material for fast and effective heavy-metal removal from aqueous solution
    Jie Cao
    Dongtao Fei
    Xiaoling Tian
    Yuejun Zhu
    Shanshan Wang
    Yadong Zhang
    Qiangqiang Mao
    Mingbo Sun
    Cellulose, 2017, 24 : 5565 - 5577
  • [44] Porous Silk Fibroin/Cellulose Hydrogels for Bone Tissue Engineering via a Novel Combined Process Based on Sequential Regeneration and Porogen Leaching
    Burger, Dennis
    Beaumont, Marco
    Rosenau, Thomas
    Tamada, Yasushi
    MOLECULES, 2020, 25 (21):
  • [45] Novel wood-based all-solid-state flexible supercapacitors fabricated with a natural porous wood slice and polypyrrole
    Lv, Shaoyi
    Fu, Feng
    Wang, Siqun
    Huang, Jingda
    Hu, La
    RSC ADVANCES, 2015, 5 (04): : 2813 - 2818
  • [46] Remediation of Cd (II) ions in aqueous and soil phases using novel porous cellulose/chitosan composite spheres loaded with zero-valent iron nanoparticles
    Li, Bo
    Li, Ming
    Zhang, Panpan
    Pan, Yuanfeng
    Huang, Zhihong
    Xiao, Huining
    REACTIVE & FUNCTIONAL POLYMERS, 2022, 173
  • [47] Development and Characterization of Celecoxib Solid Self-nanoemulsifying Drug Delivery Systems (S-SNEDDS) Prepared Using Novel Cellulose-Based Microparticles as Adsorptive Carriers
    Fabian-Pascal Schmied
    Alexander Bernhardt
    Victor Baudron
    Birte Beine
    Sandra Klein
    AAPS PharmSciTech, 23
  • [48] Development and Characterization of Celecoxib Solid Self-nanoemulsifying Drug Delivery Systems (S-SNEDDS) Prepared Using Novel Cellulose-Based Microparticles as Adsorptive Carriers
    Schmied, Fabian-Pascal
    Bernhardt, Alexander
    Baudron, Victor
    Beine, Birte
    Klein, Sandra
    AAPS PHARMSCITECH, 2022, 23 (06)
12345