OBSERVATIONS ON THE HANTZSCH REACTION - SYNTHESIS OF N-TBOC-S-DOLAPHENINE

被引：35

作者：

BREDENKAMP, MW ^{[1
]}

HOLZAPFEL, CW ^{[1
]}

SYNMAN, RM ^{[1
]}

VANZYL, WJ ^{[1
]}

机构：

[1] RAND AFRIKAANS UNIV,DEPT CHEM & BIOCHEM,POB 524,JOHANNESBURG 2006,SOUTH AFRICA

来源：

SYNTHETIC COMMUNICATIONS | 1992年 / 22卷 / 21期

关键词：

D O I：

10.1080/00397919209409251

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An understanding of the mechanism by which racemization occurs in the Hantzsch reaction preparation of 2-(1-aminoalkyl)thiazoles has enabled the development of a methodology to prevent racemization. N-t Boc-S-dolaphenine (3) is then synthesized using this methodology.

引用

页码：3029 / 3039

页数：11

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