INVESTIGATIONS OF ARISTEROMYCIN BIOSYNTHESIS - EVIDENCE FOR THE INTERMEDIACY OF A 2-ALPHA,3-ALPHA-DIHYDROXY-4-BETA-(HYDROXYMETHYL)CYCLOPENTANE-1-BETA-AMINE

被引：19
|
作者：
PARRY, RJ [1 ]
HARIDAS, K [1 ]
DEJONG, R [1 ]
JOHNSON, CR [1 ]
机构：
[1] WAYNE STATE UNIV,DEPT CHEM,DETROIT,MI 48202
来源：
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 10期
关键词：
D O I：
10.1039/c39910000740
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Administration of doubly-labelled forms of D-glucose to the fermentation broth of Streptomyces citricolor followed by isotopic trapping has provided evidence for the intermediacy of a 2-alpha,3-alpha-dihydroxy-4-beta-(hydroxymethyl)cyclopentane-1-beta-amine 7 or 8 in the biosynthesis of the nucleoside antibiotic aristeromycin 1.
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页码：740 / 741
页数：2
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