SYNTHESIS OF 1,4,5-TRISSULPHATED AND 1,4,5-TRISSULPHAMOYLATED MYO-INOSITOLS-ISOSTERIC MYOINOSITOL 1,4,5-TRISPHOSPHATE ANALOGS

被引：14
作者：
WESTERDUIN, P
WILLEMS, HAM
VANBOECKEL, CAA
机构：
[1] Akzo Pharma, Organon Scientific Development Group, 5340 BH Oss
来源：
TETRAHEDRON LETTERS | 1990年 / 31卷 / 47期
关键词：
D O I：
10.1016/S0040-4039(00)97207-1
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Synthesis of the myo-inositol 1,4,5-trisphosphate isosteric analogues (rac.) 1,4,5-trissulphate and (rac.) 1,4,5-trissulphonamido was accomplished from 1,2,4-tri-O-benzyl myo-inositol. © 1990.
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页码：6919 / 6922
页数：4
相关论文
共 20 条
[1]   RAPID FORMATION OF INOSITOL 1,3,4,5-TETRAKISPHOSPHATE FOLLOWING MUSCARINIC RECEPTOR STIMULATION OF RAT CEREBRAL CORTICAL SLICES [J].
BATTY, IR ;
NAHORSKI, SR ;
IRVINE, RF .
BIOCHEMICAL JOURNAL, 1985, 232 (01) :211-215
[2]   INOSITOL TRISPHOSPHATE, A NOVEL 2ND MESSENGER IN CELLULAR SIGNAL TRANSDUCTION [J].
BERRIDGE, MJ ;
IRVINE, RF .
NATURE, 1984, 312 (5992) :315-321
[3]   RECENT DEVELOPMENTS IN THE SYNTHESIS OF MYOINOSITOL PHOSPHATES [J].
BILLINGTON, DC .
CHEMICAL SOCIETY REVIEWS, 1989, 18 (01) :83-122
[4]   ACTIONS OF INOSITOL PHOSPHATES ON CA-2+ POOLS IN GUINEA-PIG HEPATOCYTES [J].
BURGESS, GM ;
IRVINE, RF ;
BERRIDGE, MJ ;
MCKINNEY, JS ;
PUTNEY, JW .
BIOCHEMICAL JOURNAL, 1984, 224 (03) :741-746
[5]   MYOINOSITOL 1,4,5-TRISPHOSPHOROTHIOATE - A NOVEL ANALOG OF A BIOLOGICAL 2ND MESSENGER [J].
COOKE, AM ;
GIGG, R ;
POTTER, BVL .
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1987, (20) :1525-1526
[6]   REGIOSELECTIVE MANIPULATION OF HYDROXYL-GROUPS VIA ORGANOTIN DERIVATIVES [J].
DAVID, S ;
HANESSIAN, S .
TETRAHEDRON, 1985, 41 (04) :643-663
[7]   THE ALLYL GROUP FOR PROTECTION IN CARBOHYDRATE-CHEMISTRY .18. ALLYL AND BENZYL ETHERS OF MYOINOSITOL - INTERMEDIATES FOR THE SYNTHESIS OF MYOINOSITOL TRISPHOSPHATES [J].
GIGG, J ;
GIGG, R ;
PAYNE, S ;
CONANT, R .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1987, (02) :423-429
[8]   THE ALLYL GROUP FOR PROTECTION IN CARBOHYDRATE-CHEMISTRY .20. SYNTHESIS OF 1L-1-O-METHYL-MYO-INOSITOL [(+)-BORNESITOL] BY RESOLUTION OF (+/-)-1,2,4-TRI-O-BENZYL-MYO-INOSITOL [J].
GIGG, J ;
GIGG, R ;
PAYNE, S ;
CONANT, R .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1987, (08) :1757-1762
[9]   REACTIONS OF SULFUR TRIOXIDE, AND OF ITS ADDUCTS, WITH ORGANIC COMPOUNDS [J].
GILBERT, EE .
CHEMICAL REVIEWS, 1962, 62 (06) :549-&
[10]  
IRVINE RF, 1984, BIOCHEM J, V221, P269
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