CHARACTERIZATION AND MEASUREMENT OF ANTI-IGG ANTIBODIES IN HUMAN-SERA BY RADIOIMMUNOASSAY (RIA)

被引：14

作者：

YAMAGATA, J

BARNETT, EV

KNUTSON, DW

NASU, H

CHIA, D

机构：

[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT MED,LOS ANGELES,CA 90024

[2] VET ADM WADSWORTH HOSP CTR,MED SERV,LOS ANGELES,CA 90073

[3] VET ADM WADSWORTH HOSP CTR,RES SERV,LOS ANGELES,CA 90073

来源：

JOURNAL OF IMMUNOLOGICAL METHODS | 1979年 / 29卷 / 01期

关键词：

D O I：

10.1016/0022-1759(79)90124-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A sensitive direct binding radioimmunoassay (RIA) was developed which detected low avidity anti-IgG antibodies in sera negative in the latex fixation test (LFT). IgG class antibodies could be detected and were commonly found along with IgM class antibodies. Additionally, the RIA was more reproducible than the LFT, was easily adapted to measure relative avidities of anti-IgG antibodies, and had other technical advantages over the LFT. © 1979.

引用

页码：43 / 56

页数：14

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