Comparing the Effect of Psyllium Seed on Gastroesophageal Reflux Disease With Oral Omeprazole in Patients With Functional Constipation

被引：3

作者：

Hosseini, Mousalreza ^{[1
]}

Salari, Roshanak ^{[1
]}

Rad, Mina Akbari ^{[1
]}

Salehi, Maryam ^{[1
]}

Birjandi, Batul ^{[1
]}

Salari, Masoumeh ^{[1
]}

机构：

[1] Mashhad Univ Med Sci, Mashhad, Iran

来源：

JOURNAL OF EVIDENCE-BASED INTEGRATIVE MEDICINE | 2018年 / 23卷

关键词：

gastroesophageal reflux disease; GERD; functional constipation; psyllium seed; omeprazole;

D O I：

10.1177/2515690X18763294

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases. Several studies have been carried out on the treatment of symptoms associated with GERD. The present study aimed to compare the effect of Psyllium seed and oral omeprazole on GERD in patients with functional constipation. In this trial, 132 patients were divided into 2 groups. The impact of omeprazole and Psyllium seed on the treatment and recurrence of GERD was studied. Among the patients, the rate of response to treatment was 89.2% (n = 58) in the Psyllium seed group, while in omeprazole group, it was 94% (n = 63; P = .31). The recurrence rates of Psyllium seed and omeprazole groups were 24.1% (n = 14) and 69.8% (n = 44), respectively (P < .001). The results showed that treatment of functional constipation by Psyllium seed in patients with GERD leads to improvement of GERD and its recurrences in comparison with omeprazole.

引用

页数：6

共 50 条

[21] Dilated intercellular spaces in gastroesophageal reflux disease patients and the changes of intercellular spaces after omeprazole treatment
Xue Yan
Zhou Li-Ya
Lin San-Ren
CHINESE MEDICAL JOURNAL, 2008, 121 (14) : 1297 - 1301
[22] Effect of omeprazole on acid gastroesophageal reflux and gastric acidity in preterm infants with pathological acid reflux
Omari, Taher I.
Haslam, Ross R.
Lundborg, Per
Davidson, Geoffrey P.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2007, 44 (01) : 41 - 44
[23] The Effect of Gastroesophageal Flap Valve Appearance on the Management of Patients with Symptoms of Gastroesophageal Reflux Disease
Xirouchakis, Elias
Kamberoglou, Dimitrios
Kalos, Dimitrios
Zambeli, Evanthia
Doulgeroglou, Vassilios
Tzias, Vassilios
DIGESTIVE DISEASES AND SCIENCES, 2009, 54 (02) : 328 - 332
[24] Oral pH in gastroesophageal reflux disease
Sujatha S.
Jalihal U.
Devi Y.
Rakesh N.
Chauhan P.
Sharma S.
Indian Journal of Gastroenterology, 2016, 35 (3) : 186 - 189
[25] Gastroesophageal reflux disease and oral manifestations
Romano C.
Cardile S.
Italian Journal of Pediatrics, 40 (Suppl 1) : 1 - 1
[26] COMPARISON OF OMEPRAZOLE AND RANITIDINE IN TREATMENT OF REFRACTORY GASTROESOPHAGEAL REFLUX DISEASE IN PATIENTS WITH GASTRIC-ACID HYPERSECRETION
COLLEN, MJ
STRONG, RM
DIGESTIVE DISEASES AND SCIENCES, 1992, 37 (06) : 897 - 903
[27] Oral manifestations of gastroesophageal reflux disease
Ranjitkar, Sarbin
Smales, Roger J.
Kaidonis, John A.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2012, 27 (01) : 21 - 27
[28] Electrolyte disturbances in children receiving omeprazole for gastroesophageal reflux disease
Famouri, Fatemeh
Derakhshani, Forough
Madihi, Yahya
Shahsanai, Armindokht
JOURNAL OF RESEARCH IN MEDICAL SCIENCES, 2020, 25
[29] LONG-TERM TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE WITH OMEPRAZOLE
LUNDELL, L
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 1994, 29 : 74 - 78
[30] Is the Addition of Sublingual Melatonin to Omeprazole Superior to Omeprazole Alone in the Management of Gastroesophageal Reflux Disease Symptoms: A Clinical Trial
Malekpour, Habib
Noori, Amin
Abdi, Saeed
Abbasinazari, Mohammad
Mahboubi, Arash
Ghamsari, Mahdiye Abiyar
TURKISH JOURNAL OF GASTROENTEROLOGY, 2023, 34 (12`)

← 1 2 3 4 5 →