ACUTE ZINC-CHLORIDE INGESTION IN A CHILD - LOCAL AND SYSTEMIC EFFECTS

被引：24
作者：
MCKINNEY, PE
BRENT, J
KULIG, K
机构：
来源：
ANNALS OF EMERGENCY MEDICINE | 1994年 / 23卷 / 06期
关键词：
D O I：
10.1016/S0196-0644(94)70367-1
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
A 16-month-old boy ingested liquid zinc chloride/ammonium chloride soldering flux. He developed severe local burns, metabolic acidosis, hepatic damage, hyperamylasemia, lethargy, and hypertension. Peak measured plasma zinc was 1,199 mug/dL. Because of persistent signs of systemic toxicity, he was chelated with dimercaprol (BAL) and EDTA. Although clinical improvement was noted coincident with the initiation of chelation, there was no apparent increase in urinary zinc excretion. Scarring in the gastric antrum necessitated an antrectomy. The child recovered without other apparent complications.
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页码：1383 / 1387
页数：5
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共 26 条
  • [1] Brown, Thom, Orth, Et al., Food poisoning involving zinc contamination, Arch Environ Health, 8, pp. 657-660, (1964)
  • [2] Potter, Acute zinc chloride ingestion in a child, Ann Emerg Med, 10, pp. 267-269, (1981)
  • [3] Hedtke, Daya, Neace, Et al., Local and systemic toxicity following zinc chloride ingestion (abstract), Vet Hum Toxicol, 31, (1989)
  • [4] Burkhart, Kulig, Rumack, Whole-bowel irrigation as treatment for zinc sulfate overdose, Ann Emerg Med, 19, pp. 1167-1170, (1990)
  • [5] Chobanian, Accidental ingestion of liquid zinc chloride: Local and systemic effects, Ann Emerg Med, 10, pp. 91-93, (1981)
  • [6] Murphy, Intoxication following ingestion of elemental zinc, JAMA, 212, pp. 2119-2120, (1970)
  • [7] Moore, Bleeding gastric erosion after oral zinc sulfate, BMJ, 2, (1977)
  • [8] Rumack, Spoerke, POISINDEX Information System, (1993)
  • [9] Weimar, Puhl, Smith, Et al., Zinc sulfate in acne vulgaris, Archives of Dermatology, 114, pp. 1176-1178, (1978)
  • [10] Farr, Conner, Betts, Et al., Two randomized controlled trials of zinc gluconate therapy of experimentally induced rhinovirus colds, Antimicrob Agents Chemother, 31, pp. 1183-1187, (1987)
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