Durability, safety and efficacy of polyacrylamide hydrogel (Bulkamid (R)) in the management of stress and mixed urinary incontinence: three year follow up outcomes

被引:35
作者
Pai, Aakash [1 ,2 ]
Al-Singary, Waleed [1 ]
机构
[1] Worthing Dist Hosp, Dept Urol, Worthing, England
[2] Worthing Dist Hosp, Lyndhurst Rd, Worthing, England
关键词
stress urinary incontinence; Bulkamid (R); trans-urethral injection; polyacrylamide hydrogel;
D O I
10.5173/ceju.2015.647
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Introduction There are a myriad of treatment options available for patients suffering with the increasingly prevalent condition of stress urinary incontinence (SUI). The minimally invasive nature of periurethral bulking agents makes them an attractive proposition in the correctly selected patient. There is, however, limited data available on the medium to long term safety and efficacy of this procedure. The aim of our study is to evaluate the outcomes of Polyacrylamide Hydrogel (PAHG) (Bulkamid (R)) as a periurethral bulking agent at our institution. Material and methods From 2006 to 2011, two hundred and fifty six women underwent periurethral bulking with PAHG in the management of SUI or mixed urinary incontinence (MUI). Women were assessed with at least yearly quality of life and ICIQ questionnaires. Results The majority of patients had the procedure under a local anaesthetic, with a median operative time of 9 minutes. Median follow up was 38 months. 82% of patients reported cure/significant improvement at 3 months. Importantly, this high satisfaction rate was maintained at final follow up and was reflected in both VAS and ICIQ scores. There were no reported adverse reactions and no significant safety concerns. Conclusions We conclude that Bulkamid (R) injection is an efficacious, minimally invasive, and safe procedure for a selected group of patients with stress incontinence. In our study, PAHG has been shown to be durable and safe.
引用
收藏
页码:428 / 433
页数:6
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