RELATIONSHIPS BETWEEN CHEMICAL-STRUCTURE AND BIOLOGICAL-ACTIVITY MODELED BY SIMCA PATTERN-RECOGNITION

被引：44

作者：

DUNN, WJ ^{[1
]}

WOLD, S ^{[1
]}

机构：

[1] UMEA UNIV,INST CHEM,RES GRP CHEMOMETR,S-90187 UMEA,SWEDEN

来源：

BIOORGANIC CHEMISTRY | 1980年 / 9卷 / 04期

关键词：

D O I：

10.1016/0045-2068(80)90010-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：505 / 523

页数：19

共 29 条

[1]

ALBANO C, 1978, ANAL CHIM ACTA-COMP, V103, P429

[2]

BRONSTED JN, 1928, CHEM REV, V5, P322

[3] PATTERN-RECOGNITION - CLASSIFICATION OF THERAPEUTIC AGENTS ACCORDING TO PHARMACOPHORES [J].

CAMMARATA, A ;

MENON, GK .

JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (06) :739-748

[4] PATTERN-RECOGNITION AND STRUCTURE-ACTIVITY RELATIONSHIP STUDIES - COMPUTER-ASSISTED PREDICTION OF ANTITUMOR ACTIVITY IN STRUCTURALLY DIVERSE DRUGS IN AN EXPERIMENTAL MOUSE-BRAIN TUMOR SYSTEM [J].

CHU, KC ;

FELDMANN, RJ ;

SHAPIRO, MB ;

HAZARD, GF ;

GERAN, RI .

JOURNAL OF MEDICINAL CHEMISTRY, 1975, 18 (06) :539-545

[5] DISCRIMINANT-ANALYTICAL INVESTIGATION ON THE STRUCTURAL DEPENDENCE OF HYPERGLYCEMIC AND HYPOGLYCEMIC ACTIVITY IN A SERIES OF SUBSTITUTED ORTHO-TOLUENESULFONYLTHIOUREAS AND ORTHO-TOLUENESULFONYLUREAS [J].

DOVE, S ;

FRANKE, R ;

MNDSHOJAN, OL ;

SCHKULJEV, WA ;

CHASHAKJAN, LW .

JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (01) :90-95

[6] STRUCTURE CARCINOGENICITY STUDY OF 4-NITROQUINOLINE 1-OXIDES USING SIMCA METHOD OF PATTERN-RECOGNITION [J].

DUNN, WJ ;

WOLD, S .

JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (10) :1001-1007

[7] STRUCTURE-ACTIVITY STUDY OF BETA-ADRENERGIC AGENTS USING SIMCA METHOD OF PATTERN-RECOGNITION [J].

DUNN, WJ ;

WOLD, S ;

MARTIN, YC .

JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (09) :922-930

[8]

HAMMETT LP, 1940, PHYSICAL ORGANIC CHE

[9] A QUANTITATIVE APPROACH TO BIOCHEMICAL STRUCTURE-ACTIVITY RELATIONSHIPS [J].

HANSCH, C .

ACCOUNTS OF CHEMICAL RESEARCH, 1969, 2 (08) :232-&

[10]

HANSCH C, 1962, NATURE, V194, P180

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