CENTRAL MOTOR CONDUCTION TO HAND AND LEG MUSCLES IN HUNTINGTONS-DISEASE

被引：23

作者：

HOMBERG, V

LANGE, HW

机构：

[1] Neurological Therapy Center, Department of Neurology, Heinrich Heine University, Dusseldorf

[2] Department of Psychiatry, Heinrich Heine University, Dusseldorf

来源：

MOVEMENT DISORDERS | 1990年 / 5卷 / 03期

关键词：

Corticospinal tract; Electromagnetic stimulation; Huntington's disease;

D O I：

10.1002/mds.870050305

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Using electromagnetic stimulation of motor cortex and cervical or lumbar roots, central conduction times to the thenar and abductor hallucis muscles bilaterally were determined in a population of 32 patients with definite Huntington's disease (HD) and 14 subjects at risk. The HD patients showed a wide variety of different severity of choreatic movements, disease duration, and total disability. None of the stimulation parameters (latency after cortical stimulation, amplitude, threshold, or central conduction time) revealed statistically significant abnormalities compared with a normal control group as well as between patient subgroups. The data indicate that central motor conduction to upper and lower extremity muscles remains normal in Huntington's disease irrespective of the severity of the disorder. Copyright © 1990 Movement Disorder Society

引用

页码：214 / 218

页数：5

共 28 条

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