PHOTODYNAMIC THERAPY FOR ACTINIC CHEILITIS

被引：8

作者：

Castano, E. ^{[1
]}

Comunion, A. ^{[1
]}

Arias, D. ^{[1
]}

Minano, R. ^{[1
]}

Romero, A. ^{[1
]}

Borbujo, J. ^{[1
]}

机构：

[1] Hosp Fuenlabrada, Serv Dermatol, Camino Molino 2, Madrid 28942, Spain

来源：

ACTAS DERMO-SIFILIOGRAFICAS | 2009年 / 100卷 / 10期

关键词：

actinic cheilitis; treatment; photodynamic therapy;

D O I：

10.1016/S0001-7310(09)72919-9

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Actinic cheilitis is a subtype of actinic keratosis that mainly affects the lower lip and has a higher risk of malignant transformation. Its location on the labial mucosa influences the therapeutic approach. Vermilionectomy requires local or general anesthetic and is associated with a risk of an unsightly scar, and the treatment with 5-fluorouracil or imiquimod lasts for several weeks and the inflammatory reaction can be very intense. A number of authors have used photodynamic therapy as an alternative to the usual treatments. We present 3 patients with histologically confirmed actinic cheilitis treated using photodynamic therapy with methyl aminolevulinic acid as the photosensitizer and red light at 630 nm. The clinical response was good, with no recurrences after 3 to 6 months of follow-up. Our experience supports the use of photodynamic therapy as a good alternative for the treatment of actinic cheilitis.

引用

页码：895 / 898

页数：4

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