PSAMMAPLYSIN-C - A NEW CYTOTOXIC DIBROMOTYROSINE-DERIVED METABOLITE FROM THE MARINE SPONGE DRUINELLA (=PSAMMAPLYSILLA) PURPUREA

被引：44

作者：

COPP, BR

IRELAND, CM

BARROWS, LR

机构：

[1] UNIV UTAH,DEPT MED CHEM,SALT LAKE CITY,UT 84112

[2] UNIV UTAH,DEPT PHARMACOL & TOXICOL,SALT LAKE CITY,UT 84112

来源：

JOURNAL OF NATURAL PRODUCTS | 1992年 / 55卷 / 06期

关键词：

D O I：

10.1021/np50084a021

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The new, Cytotoxic dibromotyrosine-derived metabolite psammaplysin C {3}, in addition to the two known psammaplysins A {1} and B {2}, was isolated from the marine sponge Druinella purpurea. All three compounds were found to possess moderate in vitro cytotoxicity towards the human colon tumor cell-line HCT116.

引用

页码：822 / 823

页数：2