IMIDOYLUREAS . A NEW CLASS OF ANTHELMINTICS

被引：9

作者：

DIANA, GD

YARINSKY, A

ZALAY, ES

BERBERIAN, DA

SCHALIT, S

机构：

[1] Sterling-Winthrop Research Institute, Rensselaer, New York

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1969年 / 12卷 / 05期

关键词：

D O I：

10.1021/jm00305a015

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of imidoylureas have been synthesized and examined for antihookworm activity in dogs. Among the various types prepared, the alkylimidoyl-substituted phenylureas were found most active, and 1-(p-chlorophenyl)-3-pentanimidoylurea was selected as the compound of choice, effective in a single dose of 10 mg/kg. © 1969, American Chemical Society. All rights reserved.

引用

页码：791 / +

页数：1

共 15 条

[1]

BEAVER PC, 1961, 10 WHO PUBL HEALTH P

[2]

EASSON AP T, 1931, J CHEM SOC, P2991

[3]

ERDMANN H, 1897, J PRAKT CHEM, V56, P6

[4] STEREOCHEMISCHE UNTERSUCHUNGEN BEI DITHIAZOLYLEN [J].