PHARMACOKINETIC AND METABOLIC STUDIES OF HYPOXIC CELL RADIOSENSITIZER MISONIDAZOLE

被引：90

作者：

FLOCKHART, IR ^{[1
]}

LARGE, P ^{[1
]}

TROUP, D ^{[1
]}

MALCOLM, SL ^{[1
]}

MARTEN, TR ^{[1
]}

机构：

[1] ROCHE PROD LTD,WELWYN GARDEN CTY AL7 3AY,ENGLAND

来源：

XENOBIOTICA | 1978年 / 8卷 / 02期

关键词：

D O I：

10.3109/00498257809060388

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：97 / 105

页数：9

共 9 条

[1] ELECTRON-AFFINIC SENSITIZATION .7. CORRELATION BETWEEN STRUCTURES ONE-ELECTRON REDUCTION POTENTIALS, AND EFFICIENCIES OF NITROIMIDAZOLES AS HYPOXIC CELL RADIOSENSITIZERS [J].

ADAMS, GE ;

FLOCKHART, IR ;

SMITHEN, CE ;

STRATFORD, IJ ;

WARDMAN, P ;

WATTS, ME .

RADIATION RESEARCH, 1976, 67 (01) :9-20

[2]

ADAMS GE, 1976, MODIFICATION RADIOSE, P103

[3]

DeSilva J A, 1970, J Pharm Sci, V59, P201, DOI 10.1002/jps.2600590213

[4] CLINICAL TESTING OF RADIOSENSITIZER RO 07-0582 - EXPERIENCE WITH MULTIPLE DOSES [J].

DISCHE, S ;

SAUNDERS, MI ;

LEE, ME ;

ADAMS, GE ;

FLOCKHART, IR .

BRITISH JOURNAL OF CANCER, 1977, 35 (05) :567-579

[5] CLINICAL TESTING OF RADIOSENSITIZER RO-07-0582 .1. DOSE TOLERANCE, SERUM AND TUMOR CONCENTRATIONS [J].

GRAY, AJ ;

DISCHE, S ;

ADAMS, GE ;

FLOCKHART, IR ;

FOSTER, JL .

CLINICAL RADIOLOGY, 1976, 27 (02) :151-157

[6]

JOHNSON R, 1976, BRIT J RADIOL, V49, P294, DOI 10.1259/0007-1285-49-579-294-b

[7]

KANE PO, 1961, J POLAR SOC, V7, P58

[8] HYPOXIC CELL RADIOSENSITIZERS AND LOCAL CONTROL BY X-RAY OF A TRANSPLANTED TUMOR IN MICE [J].

SHELDON, PW ;

HILL, SA .

BRITISH JOURNAL OF CANCER, 1977, 35 (06) :795-808

[9] CLINICAL PHASE-1 STUDY OF HYPOXIC CELL RADIOSENSITIZER RO-07-0582, A 2-NITROIMIDAZOLE DERIVATIVE [J].

URTASUN, RC ;

BAND, P ;

CHAPMAN, JD ;

RABIN, HR ;

WILSON, AF ;

FRYER, CG .

RADIOLOGY, 1977, 122 (03) :801-804

← 1 →