Personalized Health Care as a Pathway for the Adoption of Genomic Medicine

被引:15
作者
Burnette, Robin [1 ,2 ]
Simmons, Leigh Ann [1 ,3 ]
Snyderman, Ralph [1 ,4 ]
机构
[1] Duke Univ, Med Ctr, Duke Ctr Res Prospect Hlth Care, Durham, NC 27701 USA
[2] Duke Univ, Med Ctr, Dept Community & Family Med, Durham, NC 27701 USA
[3] Duke Univ, Med Ctr, Sch Nursing, Durham, NC 27701 USA
[4] Duke Univ, Med Ctr, Dept Med, Durham, NC 27701 USA
关键词
personalized health plan; multi-morbidities; preventive; health risk assessment; chronic disease management; personalized medicine tools; genomic medicine;
D O I
10.3390/jpm2040232
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
While the full promise of genomic medicine may be many years in the future, personalized health care (PHC) can begin solving important health care needs now and provide a framework for the adoption of genomic technologies as they are validated. PHC is a strategic approach to medicine that is individualized, predictive, preventive, and involves intense patient engagement. There is great need for more effective models of care as nearly half of Medicare patients age 65 and older have three or more preventable chronic conditions and account for 89% of Medicare's growing expenditures. With its focus on reactive care, the current health care system is not designed to effectively prevent disease nor manage patients with multiple chronic conditions. PHC may be a solution for improving care for this population and therefore has been adopted as the delivery platform along with a new personalized health plan tool for 230 multi-morbid, homebound Medicare recipients in Durham, North Carolina who have been high utilizers of health care resources. PHC integrates available personalized health technologies, standards of care, and personalized health planning to serve as a model for rational health care delivery. Importantly, the PHC model of care will serve as a market for emerging predictive and personalized technologies to foster genomic medicine.
引用
收藏
页码:232 / 240
页数:9
相关论文
共 19 条
[1]   Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study [J].
Barnett, Karen ;
Mercer, Stewart W. ;
Norbury, Michael ;
Watt, Graham ;
Wyke, Sally ;
Guthrie, Bruce .
LANCET, 2012, 380 (9836) :37-43
[2]   Commentary: Personalized Health Planning and the Patient Protection and Affordable Care Act: An Opportunity for Academic Medicine to Lead Health Care Reform [J].
Dinan, Michaela A. ;
Simmons, Leigh Ann ;
Snyderman, Ralph .
ACADEMIC MEDICINE, 2010, 85 (11) :1665-1668
[3]   The genome gets personal - Almost [J].
Feero, W. Gregory ;
Guttmacher, Alan E. ;
Collins, Francis S. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2008, 299 (11) :1351-1352
[4]   Revolutionizing medicine in the 21st century through systems approaches [J].
Hood, Leroy ;
Balling, Rudi ;
Auffray, Charles .
BIOTECHNOLOGY JOURNAL, 2012, 7 (08) :992-1001
[5]   Predictive, personalized, preventive, participatory (P4) cancer medicine [J].
Hood, Leroy ;
Friend, Stephen H. .
NATURE REVIEWS CLINICAL ONCOLOGY, 2011, 8 (03) :184-187
[6]   AN OVERVIEW OF RISK ASSESSMENT IN CORONARY-ARTERY DISEASE [J].
MARK, DB .
AMERICAN JOURNAL OF CARDIOLOGY, 1994, 73 (06) :B19-B25
[7]  
Montgomery L., 2011, WASHINGTON POST
[8]   A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance [J].
Newgard, Christopher B. ;
An, Jie ;
Bain, James R. ;
Muehlbauer, Michael J. ;
Stevens, Robert D. ;
Lien, Lillian F. ;
Haqq, Andrea M. ;
Shah, Svati H. ;
Arlotto, Michelle ;
Slentz, Cris A. ;
Rochon, James ;
Gallup, Dianne ;
Ilkayeva, Olga ;
Wenner, Brett R. ;
Yancy, William S., Jr. ;
Eisenson, Howard ;
Musante, Gerald ;
Surwit, Richard S. ;
Millington, David S. ;
Butler, Mark D. ;
Svetkey, Laura P. .
CELL METABOLISM, 2009, 9 (04) :311-326
[9]   Multimorbidity: redesigning health care for people who use it [J].
Salisbury, Chris .
LANCET, 2012, 380 (9836) :7-9
[10]  
Simmons LA, 2012, PERS MED, V9, P85, DOI [10.2217/PME.11.86, 10.2217/pme.11.86]