POTENTIATION OF ACETALDEHYDE-INDUCED VASOCONSTRICTIONS BY COCAINE IN ISOLATED AND PERFUSED ARTERIES

被引：2
|
作者：
CHIBA, S
TSUKADA, M
机构：
[1] Department of Pharmacology, Shinshu University School of Medicine
来源：
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE | 1991年 / 165卷 / 01期
关键词：
ACETALDEHYDE; COCAINE; CANNULA INSERTING METHOD;
D O I：
10.1620/tjem.165.63
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Vasoconstrictor responses to acetaldehyde (AA), norepinephrine (NE) and tyramine were investigated in isolated, perfused canine intermediate auricular (ear) arteries. Single injections of small doses of AA (1-3-mu-mol) induced a vasoconstriction in a dose-related manner and showed no tachyphylaxis. Cocaine significantly inhibited tyramine-induced vasoconstrictions, but NE- and AA-induced vasoconstrictions were rather significantly enhanced.
引用
收藏
页码：63 / 65
页数：3
相关论文
共 50 条
  • [1] CHARACTERISTICS OF HISTAMINE-INDUCED VASOCONSTRICTIONS IN ISOLATED AND PERFUSED CANINE FEMORAL ARTERIES AND VEINS
    KAWAI, K
    CHIBA, S
    ASIA PACIFIC JOURNAL OF PHARMACOLOGY, 1989, 4 (04): : 323 - 328
  • [2] POTENTIATING EFFECT OF TYRAMINE ON ACETALDEHYDE-INDUCED VASOCONSTRICTION IN ISOLATED DOG MESENTERIC-ARTERIES
    CHIBA, S
    TSUKADA, M
    JAPANESE JOURNAL OF PHARMACOLOGY, 1987, 44 (03): : 365 - 368
  • [3] ACETALDEHYDE-INDUCED LIPID PEROXIDATION IN ISOLATED HEPATOCYTES
    STEGE, TE
    DANIELS, SE
    STURTZ, J
    FEDERATION PROCEEDINGS, 1978, 37 (03) : 303 - 303
  • [4] ACETALDEHYDE-INDUCED LIPID-PEROXIDATION IN ISOLATED HEPATOCYTES
    STEGE, TE
    RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY, 1982, 36 (02): : 287 - 297
  • [5] ACETALDEHYDE-INDUCED RELEASE OF CATECHOLAMINES FROM ISOLATED BOVINE ADRENAL MEDULLA
    SCHNEIDER, FH
    PHARMACOLOGIST, 1969, 11 (02): : 262 - +
  • [6] Perivascular purinergic nerve-induced vasoconstrictions in canine isolated splenic arteries
    Yang, XP
    Chiba, S
    JAPANESE JOURNAL OF PHARMACOLOGY, 2000, 82 (01): : 71 - 73
  • [7] Phosphofructokinase controls the acetaldehyde-induced phase shift in isolated yeast glycolytic oscillators
    van Niekerk, David D.
    Gustavsson, Anna-Karin
    Mojica-Benavides, Martin
    Adiels, Caroline B.
    Goksor, Mattias
    Snoep, Jacky L.
    BIOCHEMICAL JOURNAL, 2019, 476 : 353 - 363
  • [8] IMPROVED SEPARATION OF ACETALDEHYDE-INDUCED HEMOGLOBIN
    HAZELETT, SE
    LIEBELT, RA
    TRUITT, EB
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 1993, 17 (05) : 1107 - 1111
  • [9] Pressor response to acetaldehyde and its potentiation by cocaine
    Nelson, EE
    PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE, 1943, 52 (01): : 23 - 24
  • [10] ACETALDEHYDE-INDUCED CORONARY VASODILATION IN CONSCIOUS DOGS
    STRATTON, R
    GWIRTZ, P
    DORMER, KJ
    FEDERATION PROCEEDINGS, 1981, 40 (03) : 729 - 729
12345