EXTRACTION AND HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF ENDOFLOXACIN IN FISH SERUM AND TISSUES

被引：17
|
作者：
ROGSTAD, A [1 ]
HORMAZABAL, V [1 ]
YNDESTAD, M [1 ]
机构：
[1] NORWEGIAN COLL VET MED,DEPT FOOD HYG,N-0033 OSLO 1,NORWAY
来源：
JOURNAL OF LIQUID CHROMATOGRAPHY | 1991年 / 14卷 / 03期
关键词：
D O I：
10.1080/01483919108049267
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The extraction of enrofloxacin from fish serum and tissues using solid phase extraction columns has been studied. Good recoveries were obtained by using C2 columns for clean-up of serum and C18 columns for clean-up of tissue samples. The sample pretreatment procedures are selective and robust having a sensitivity of 1 ng/ml and 1 ng/g from serum and tissues, respectively, making them particularly useful for monitoring drug residue levels. The recoveries were 97-100% from serum and 96-99% from tissues. The method was tested on fish treated with enrofloxacin.
引用
收藏
页码：521 / 531
页数：11
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